The short answer
Doing it in the print dialog works once, on your printer. Building it into the PDF makes the layout part of the document, so it prints the same way for everyone you send it to — which is what you want for a handout.
Step by step
- Choose the layout for the content Two-up keeps most documents comfortably readable. Four-up suits slides with large type. Six-up is for reference sheets, not for anything anyone has to read closely.
- Check the orientation Two portrait pages sit best side by side on a landscape sheet. The tool handles the rotation; the point is to check it went the way you expected.
- Look at the smallest text Footnotes and figure captions are what make a four-up handout unusable. If they are marginal on screen, they will be worse on paper.
- Save and print from the new file Print at 100% with scaling off — letting the printer shrink an already-shrunk layout is what produces unreadable handouts.
Questions
Why not just use the printer’s N-up setting?
It only applies to that print job on that machine. Building it into the PDF means anyone who prints the file gets the same layout, which matters for a handout you are sending out.
How many pages per sheet is still readable?
Two-up is safe for almost anything. Four-up works for slides and large type. Six-up and beyond is reference-only — print one test page before committing a class set.
Does this reduce the file size?
Not meaningfully. The same content is arranged differently on fewer, larger pages. It saves paper, not megabytes.
More in Merge & Organize PDF Pages .